MATERIAU DE SUTURE DE PLAIES A BASE DE METHYLIDENE MALONATE

• Main Authors: BRU MAGNIEZ NICOLE, BELIARD ISABELLE, BRETON PASCAL, ROQUES CARMES CLAUDE
• Format: Patent
• Language: French
• Published: 27.04.2001
• Edition: 7
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP

A method for the suture of wounds, includes applying a sufficient quantity of a biocompatible, bio-adhesive mixture with at least 50% by weight of a methylidene malonate-based composition containing:40 to 100% by weight of at least one methylidene malonate of formula (I): in which:A and B independently represent a group (a) or (b):in which R1 and R2 independently represent a linear or branched alkyl group with 1 to 6 carbon atoms, n is an integer between 1 and 5, and at least one of A and B represents a (b) group;and/or one or more methylidene malonate oligomers with a molecular weight less than or equal to 6,000 and including recurrent units of formula (II):in which A and B are as defined above; and0 to 60% by weight of at least one methylidene malonate polymer with a molecular weight greater than 6,000 and including recurrent units of formula (II).