PROCEDE D'EXTRACTION ET D'ISOLEMENT DE LA 10-DESACETYLBACCATINE III

A method for extracting and isolating 10-deacetylbaccatin III (tetraol) from yew leaves, comprising a first step of extracting yew leaves using a suitable protic solvent to give an aqueous extract, followed by a second step of extracting the aqueous extract using a suitable organic solvent to cause...

Full description

Saved in:
Bibliographic Details
Main Authors DAVID BRUNO, NEGOL PAUL, SERRANO MARIE JEANNE
Format Patent
LanguageFrench
Published 07.11.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:A method for extracting and isolating 10-deacetylbaccatin III (tetraol) from yew leaves, comprising a first step of extracting yew leaves using a suitable protic solvent to give an aqueous extract, followed by a second step of extracting the aqueous extract using a suitable organic solvent to cause selective crystallisation of the tetraol, and a final step of isolating the tetraol by selective crystallisation from the resulting organic phase. A final purification step enables a product with a titre of almost 100 % to be achieved.
Bibliography:Application Number: FR19950008241