Activité hémostatique et stabilisatrice des vaisseaux capillaires de dérivés de l'adrénochrome
The invention comprises adrenochrome monoaminoguanidine and salts thereof with hydrohalic acids, monocarboxylic and sulphonic acids. The compound is prepared by mixing an aqueous solution of adrenochrome with a salt of aminoguanidine, e.g. the nitrate, together with a sufficient amount of a mineral...
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| Main Author | |
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| Format | Patent |
| Language | French |
| Published |
27.07.1964
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The invention comprises adrenochrome monoaminoguanidine and salts thereof with hydrohalic acids, monocarboxylic and sulphonic acids. The compound is prepared by mixing an aqueous solution of adrenochrome with a salt of aminoguanidine, e.g. the nitrate, together with a sufficient amount of a mineral acid to catalyse the reaction, and rendering the solution alkaline with ammonia or caustic soda to precipitate an orange-coloured product. The compound may be refined by dissolving in aqueous acetic acid and precipitating with caustic soda. Adrenochrome monoaminoguanidine and its salts have homostatic and capillary-stabilizing actions and are used in aqueous solutions as injections. |
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| AbstractList | The invention comprises adrenochrome monoaminoguanidine and salts thereof with hydrohalic acids, monocarboxylic and sulphonic acids. The compound is prepared by mixing an aqueous solution of adrenochrome with a salt of aminoguanidine, e.g. the nitrate, together with a sufficient amount of a mineral acid to catalyse the reaction, and rendering the solution alkaline with ammonia or caustic soda to precipitate an orange-coloured product. The compound may be refined by dissolving in aqueous acetic acid and precipitating with caustic soda. Adrenochrome monoaminoguanidine and its salts have homostatic and capillary-stabilizing actions and are used in aqueous solutions as injections. |
| Author | YAMANISHI YASUHITO |
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| Notes | Application Number: FR19630935959 |
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| PublicationDate | 19640727 |
| PublicationDateYYYYMMDD | 1964-07-27 |
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| PublicationDecade | 1960 |
| PublicationYear | 1964 |
| RelatedCompanies | SHIRAIMATSU-SHINYAKU KABUSHIKI KAISHA |
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| Snippet | The invention comprises adrenochrome monoaminoguanidine and salts thereof with hydrohalic acids, monocarboxylic and sulphonic acids. The compound is prepared... |
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| Title | Activité hémostatique et stabilisatrice des vaisseaux capillaires de dérivés de l'adrénochrome |
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