Activité hémostatique et stabilisatrice des vaisseaux capillaires de dérivés de l'adrénochrome

The invention comprises adrenochrome monoaminoguanidine and salts thereof with hydrohalic acids, monocarboxylic and sulphonic acids. The compound is prepared by mixing an aqueous solution of adrenochrome with a salt of aminoguanidine, e.g. the nitrate, together with a sufficient amount of a mineral...

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Bibliographic Details
Main Author YAMANISHI YASUHITO
Format Patent
LanguageFrench
Published 27.07.1964
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention comprises adrenochrome monoaminoguanidine and salts thereof with hydrohalic acids, monocarboxylic and sulphonic acids. The compound is prepared by mixing an aqueous solution of adrenochrome with a salt of aminoguanidine, e.g. the nitrate, together with a sufficient amount of a mineral acid to catalyse the reaction, and rendering the solution alkaline with ammonia or caustic soda to precipitate an orange-coloured product. The compound may be refined by dissolving in aqueous acetic acid and precipitating with caustic soda. Adrenochrome monoaminoguanidine and its salts have homostatic and capillary-stabilizing actions and are used in aqueous solutions as injections.
Bibliography:Application Number: FR19630935959