PROCEDE DE PREPARATION D'UNE FRACTION CONCENTREE EN FACTEUR VIIA ET SON APPLICATION A TITRE DE MEDICAMENT

The invention described is characterized in that: the pre-eluate of the PPSB is adsorbed by an absorber having a selective affinity for proteins which attach to calcium, selected among bivalent metal salts insoluble in water; the fixed proteins are eluated by addition of a buffer containing soluble...

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Bibliographic Details
Main Authors MARION STEINBUCH, LUCETTE PEJAUDIER, JACQUES CHABBAT
Format Patent
LanguageFrench
Published 13.03.1992
Edition4
Subjects
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Summary:The invention described is characterized in that: the pre-eluate of the PPSB is adsorbed by an absorber having a selective affinity for proteins which attach to calcium, selected among bivalent metal salts insoluble in water; the fixed proteins are eluated by addition of a buffer containing soluble salts able to shift the fixed proteins; the eluate-rich in fractor VIIa is recovered.
Bibliography:Application Number: FR19880007687