DERIVES DU TAXOL, LEUR PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT

NOUVEAUX DERIVES DU TAXOL DE FORMULE GENERALE I DANS LAQUELLE R REPRESENTE HYDROGENE OU ACETYLE, UN DES SYMBOLES R OU R REPRESENTE HYDROXY ET L'AUTRE REPRESENTE TERTIOBUTOXYCARBONYLAMINO ET LEURS ISOMERES, LEUR PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT. Taxol derivativ...

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Bibliographic Details
Main Author MICHEL COLIN, DANIEL GUENARD, FRANCOISE GUERITTE-VOEGELEIN ET PIERRE POTIER
Format Patent
LanguageFrench
Published 22.01.1988
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:NOUVEAUX DERIVES DU TAXOL DE FORMULE GENERALE I DANS LAQUELLE R REPRESENTE HYDROGENE OU ACETYLE, UN DES SYMBOLES R OU R REPRESENTE HYDROXY ET L'AUTRE REPRESENTE TERTIOBUTOXYCARBONYLAMINO ET LEURS ISOMERES, LEUR PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT. Taxol derivatives of formula I in which R represents hydrogen or acetyl, one of R1 or R2 represents hydroxy and the other represents tert-butoxycarbonylamino and their isomers are useful antitumor agents.
Bibliography:Application Number: FR19860010400