PROCEDE DE PREPARATION DE 4-(2-PHENOXYETHYL)-1,2,4-TRIAZOLONE

In a novel process for the preparation of 5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazolone (used in the synthesis of antidepressant 1,2,4-triazolones typified by 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one, also known as nefazodone), novel interme...

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Bibliographic Details
Main Author GARY D. MADDING
Format Patent
LanguageFrench
Published 27.02.1987
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:In a novel process for the preparation of 5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazolone (used in the synthesis of antidepressant 1,2,4-triazolones typified by 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one, also known as nefazodone), novel intermediate acid addition salts of formula and processes for their preparation are disclosed.y
Bibliography:Application Number: FR19840018173