NOUVEAUX ANALOGUES ANTAGONISTES DE L'ANGIOTENSINE II CONTENANT UN OXACIDE A-AMINE EN POSITION 1

L'invention concerne des composés chimiques nouveaux. Il s'agit de peptides de formule générale : Angiotensin II analog of the formula I X-Arg-Val-Tyr-Ile-His-Pro-Y(I) wherein X is a radical derived from an aliphatic alpha -aminooxy-carboxylic acid and Y is a radical derived from an alipha...

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Main Author LAJOS KISFALUDY, GYORGY NYEKI, LASZLO SZIRMAI, EGON KARPATI, KATALIN GIDAI ET LASZLO SZPORNY
Format Patent
LanguageFrench
Published 16.02.1979
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:L'invention concerne des composés chimiques nouveaux. Il s'agit de peptides de formule générale : Angiotensin II analog of the formula I X-Arg-Val-Tyr-Ile-His-Pro-Y(I) wherein X is a radical derived from an aliphatic alpha -aminooxy-carboxylic acid and Y is a radical derived from an aliphatic alpha -amino-carboxylic acid, and acid addition salts and complexes thereof with antagonistic properties useful in the diagnosis and treatment of hypertensions depending on renin.
Bibliography:Application Number: FR19780021136