NOUVEL ALCALOIDE DIINDOLIQUE ET PROCEDE DE PREPARATION DE CE COMPOSE

4-Deacetoxyvincristine and acid addition salts of this compound are obtained by subjecting 4-deacetoxyvinblastine to oxydative formylation and converting the resulting compound where appropriate into its acid addition salts. This compound which can be prepared according to the invention has, for exa...

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Main Author KAROLA JOVANOVICS, LAJOS DANCSI, SANDOR ECKHARDT, CSABA LORINCZ, JANOS SUGAR, ZSUZSA RELLE NEE SOMFAI, KALMAN SZASZ, JOZSEF TAMAS ET ARON SZOLLOSY
Format Patent
LanguageFrench
Published 23.09.1977
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Summary:4-Deacetoxyvincristine and acid addition salts of this compound are obtained by subjecting 4-deacetoxyvinblastine to oxydative formylation and converting the resulting compound where appropriate into its acid addition salts. This compound which can be prepared according to the invention has, for example, excellent cytostatic properties and is less toxic than vincristine, which has similar actions.
Bibliography:Application Number: FR19770005059