Functional fluorinated derivatives prepn. - by transformation of a (1)-hydrogen-perfluoroalkyl gp. under mild conditions

A fluorinated cpd. Y-CHF-(CH2)n-1X(1) (where X is F or an organic gp. Y is a functional organic gp. and n is an integer) is prepd. by reacting HCF2-(CF2)n-X'(II) (where X' is an opt. protected X gp.) with R2NM, (where M is alkali(ne-earth) metal and R is a hydrocarbon gp). The reaction tak...

Full description

Saved in:
Bibliographic Details
Main Author CLAUDE WAKSELMAN ET NGUYEN THOAI
Format Patent
LanguageEnglish
French
Published 16.09.1977
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:A fluorinated cpd. Y-CHF-(CH2)n-1X(1) (where X is F or an organic gp. Y is a functional organic gp. and n is an integer) is prepd. by reacting HCF2-(CF2)n-X'(II) (where X' is an opt. protected X gp.) with R2NM, (where M is alkali(ne-earth) metal and R is a hydrocarbon gp). The reaction takes place at -100 to +20 degrees C in a solvent which is a dialkyl ether, cyclic ether e.g. THF, polyethylene glycol ether, a hydrocarbon, or a mixt. of these different solvents. The reaction prod. is hydrolysed in acid medium giving R2N-CO-CHF(CF2)n-1X'. If necessary X' is de-protected and R2N-CO- is transformed to another functional gp. Y. The process allows the transformation of a 1H-perfluoroalkyl gp. under muld conditions, giving a large variety of fluorinated derivs. carrying functional gps. (I) are esp. useful for prodn. of fluorinated polymers used for protecting surfaces.
Bibliography:Application Number: FR19760004711