Uudet 3-(substituoitu tetratsolyyli)-4-okso-4H-pyrido/1,2-a/pyrimidiinit, niiden suolat, niitä sisältävät farmaseuttiset koostumukset ja niiden valmistusmenetelmä

PCT No. PCT/HU92/00031 Sec. 371 Date Feb. 10, 1994 Sec. 102(e) Date Feb. 10, 1994 PCT Filed Aug. 13, 1992 PCT Pub. No. WO93/04065 PCT Pub. Date Mar. 4, 1993.4-oxo-4H-pyrido[1,2-a]-pyrimidines are disclosed of the formula (I) and/or (II) wherein R is a C1-6alkyl, C3-6alkenyl, C3-6alkynyl, C3-7 cycloa...

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Main Authors KNOLL, JOZSEF, VASVARI, LELLE, BALOGH, MARIA, GYIRES, KLARA, KAPUI, ZOLTAN, PAPP, ILONA, HORVATH, AGNES, HERMECZ, ISTVAN, SIPOS, JUDIT, TARDOS, LASZLO
Format Patent
LanguageFinnish
Swedish
Published 09.02.1994
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PCT No. PCT/HU92/00031 Sec. 371 Date Feb. 10, 1994 Sec. 102(e) Date Feb. 10, 1994 PCT Filed Aug. 13, 1992 PCT Pub. No. WO93/04065 PCT Pub. Date Mar. 4, 1993.4-oxo-4H-pyrido[1,2-a]-pyrimidines are disclosed of the formula (I) and/or (II) wherein R is a C1-6alkyl, C3-6alkenyl, C3-6alkynyl, C3-7 cycloalkyl, -(CH2)n-COOR3 wherein R3 is C1 to C4 alkyl and n is 0 or 1 or a C7-8 aralkyl group, optionally substituted by one or more halogen atom(s), or by a nitro-group, R1 is a hydrogen atom or a C1-4 alkyl group, and salts thereof, as well as a process for their preparation, and pharmaceutical compositions containing them. These compounds are therapeutically useful as gastroprotectives in the treatment and prevention of ulcer.
Bibliography:Application Number: FI19940000591