Foerriktning av bindningspar in vivo

A method for in-vivo targeting a functional moiety in a patient by administering a targeting moiety coupled to an affinity component, wherein the targeting moiety has affinity for binding sites in a target area, and administering a binding partner to the affinity component coupled to a functional mo...

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Bibliographic Details
Main Authors VOGEL, CARL-WILHELM ERNST, KIM, CHONG-HO, BREDEHORST, REINHARD, MCCABE, RICHARD P, HAWKINS, GREGORY ALAN, POMATO, NICHOLAS
Format Patent
LanguageFinnish
Published 03.11.1993
Edition5
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A method for in-vivo targeting a functional moiety in a patient by administering a targeting moiety coupled to an affinity component, wherein the targeting moiety has affinity for binding sites in a target area, and administering a binding partner to the affinity component coupled to a functional moiety to localize the functional moiety in the target area. Preferably the targeting moiety is an antibody and the functional moiety is a radiometal when performing in vivo imaging or therapy. The affinity component may be a novel methotrexate analog.
Bibliography:Application Number: FI19930004857