SULFONAMIDDERIVAT
To provide new sulfonamide derivatives having an excellent antitumor activity and only a low toxicity and a process for producing them. Sulfonamide derivatives of the general formula (I): wherein preferably R represents a lower alkoxy group, R , R , R , R , R and R may be the same or different from...
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Main Authors | , , , , , , , , , , , , , |
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Format | Patent |
Language | Finnish |
Published |
21.02.1992
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Edition | 5 |
Subjects | |
Online Access | Get full text |
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Summary: | To provide new sulfonamide derivatives having an excellent antitumor activity and only a low toxicity and a process for producing them. Sulfonamide derivatives of the general formula (I): wherein preferably R represents a lower alkoxy group, R , R , R , R , R and R may be the same or different from one another and each represent a hydrogen atom, halogen atom or lower alkyl group, A and B may be the same or different from each other and each represent =N- or =CH-, E represents an aromatic 6-membered cyclic group (which may have 1 or 2 nitrogen atoms in the ring) which may be substituted with 1 to 3 substituents which may be the same or different from one another with the proviso that a combination of R which is a hydrogen atom, lower alkyl group, nitro group or amino group which may be protected, R and R which are each a hydrogen atom, A and B which are each =CH- and E which is a phenyl group which may be substituted with 1 to 3 substituents G which may be the same or different from one another is excluded, or pharmacologically acceptance salts of them. |
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Bibliography: | Application Number: FI19910003815 |