Menetelmä lääkeaineena käyttökelpoisten piperidiinijohdannaisten valmistamiseksi

Heterocyclic amines of formula (I) and their salts are new: where A is (opt. substd.) phenyl or naphthyl, pyridyl, thienyl, tetralyl, quinolinyl, benzofuranyl, quinazolinyl, benzothienyl, 1,2,3,4-tetrahydro-2-quinolinyl or 1-oxo-1,2,3,4-tetrahydro -2-naphthyl; X is -CH2, -CO-, -CHOH-, -CHMe- or -CH(...

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Main Authors YONAGA,MASAHIRO, KARIBE,NORIO, HIGURASHI,KUNIZOU, SAITO,ISAO, KANEKO,TAKERU, NAKAZAWA,TAKAHIRO, UENO,MASATAKA, SUGIMOTO,HACHIRO, NAKAMURA,TAKAHARU, YAMATSU,KIYOMI
Format Patent
LanguageFinnish
Swedish
Published 25.02.1994
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Heterocyclic amines of formula (I) and their salts are new: where A is (opt. substd.) phenyl or naphthyl, pyridyl, thienyl, tetralyl, quinolinyl, benzofuranyl, quinazolinyl, benzothienyl, 1,2,3,4-tetrahydro-2-quinolinyl or 1-oxo-1,2,3,4-tetrahydro -2-naphthyl; X is -CH2, -CO-, -CHOH-, -CHMe- or -CH(CH2NEt2)-; m is 1-3; n is 0-4; Y is C or N; Z is -CH2-, -CO-, -CHOR1-, -CHHal-, -CH=, or a group of formula (II), (III) or (IV); R1 is H, lower alkyl, acyl, aralkyl or heteroaralkyl, Hal is halogen; B is phenyl or naphthyl opt. substd. by one or two groups chosen from halogen, lower alkyl or lower alkoxy; Z-B may be bound at either of the positions starred on the ring.
Bibliography:Application Number: FI19880002369