Menetelmä terapeuttisesti aktiivisten 8-aminosubstituoitu-7,8-dihydro-6,6-dimetyyli-6H-pyrano/2,3-f/bentso-2,1,3-oksadiatsolien valmistamiseksi

The invention includes compounds of the formula (I): wherein A represents OH or OC(O)CH3-nXn, B represents hydrogen atom, or A and B together represent a bond; R represents hydrogen atom, R represents hydrogen atom, C(Z)CH3-nXn or C(Z)NHCH3-nXn or R and R together represents (CH2)m, (CH2)m-1C(Z), N(...

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Bibliographic Details
Main Authors RYOZO, SAKODA, YUKINORI, MASUDA, HIROO, MATSUMOTO, KIYOTOMO, SETO, KAZUHIKO, OHRAI, YOSHIMASA, KAMIKAWAJI, KOYKO, NAKAYAMA
Format Patent
LanguageFinnish
Swedish
Published 25.09.1989
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention includes compounds of the formula (I): wherein A represents OH or OC(O)CH3-nXn, B represents hydrogen atom, or A and B together represent a bond; R represents hydrogen atom, R represents hydrogen atom, C(Z)CH3-nXn or C(Z)NHCH3-nXn or R and R together represents (CH2)m, (CH2)m-1C(Z), N(R )(CH2)2C(Z), (CH2)m-2NHC(Z) or (CH2)m-2OC(Z) in which X represents fluorine atom, chlorine atom, bromine atom, a methyl group or a methoxy group and n represents 0 or an integer of 1 to 3, Z represents oxygen atom or sulfur atom, m represents an integer of 4 or 5 and R represents hydrogen atom or a methyl group, and pharmacological acceptable salts of the compounds which can form salts, preparation methods therefor, pharmaceutical use of the compounds and compositions comprising the compounds.
Bibliography:Application Number: FI19890004520