FRAMSTAELLNING AV NYA HETEROCYKLISKA FOERENINGAR MED ANTIALLERGISK OCH ANTITROMBOTISK VERKAN

Heterocycles of formula (I) and their pharmaceutically acceptable salts are new, Z = N W =CHR2 when n = 0 or CR2 or CHR2 when n = 1; Y = CH2O, OCH2, CH2S, SCH2, CH2N(R2), N(R2)CH2, CON(R2) or N(R2)CO; n = 0 or 1; R1 = H, lower alkyl, lower alkoxy, lower alkanoyl, halo, CF3, NO2 or CN; R2 = H or lowe...

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Bibliographic Details
Main Authors MUSSER, JOHN HENRY, KUBRAK, DENNIS MARTIN, KREFT III, ANTHONY FRANK
Format Patent
LanguageFinnish
Published 28.07.1987
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Heterocycles of formula (I) and their pharmaceutically acceptable salts are new, Z = N W =CHR2 when n = 0 or CR2 or CHR2 when n = 1; Y = CH2O, OCH2, CH2S, SCH2, CH2N(R2), N(R2)CH2, CON(R2) or N(R2)CO; n = 0 or 1; R1 = H, lower alkyl, lower alkoxy, lower alkanoyl, halo, CF3, NO2 or CN; R2 = H or lower alkyl; R3 = lower alkyl, lower perfluoroalkyl or perfluorophenyl, halo = F, Cl or Br; lower alkyl or alkoxy = 1-6C; lower alkanoyl = 2-6C. Specifically claimed are 3 cpds. (I) viz. N-(3-((2-quinolyl) methoxy)phenyl)ethane sulphonamide, N-(3-((2-quinolyl) methoxy) phenyl) -1-butanesulphonamide and N-(3-((2-quinolyl) methoxy) phenyl) trifluoromethane sulphonamide (Ia).
Bibliography:Application Number: FI19870000298