FOERFARANDE FOER UTVINNANDE AV FOER NATURLIG OCH KONSTGJORD BEFRUKTNING LAEMPADE FORTPLANTNINGSPRODUKTER FRAON DAEGGDJUR

• Main Authors: BANHAZI, CSABA, KERI, GYOERGY, TEPLAN, ISTVAN, HORVATH, ANIKO, KOVATS, ESZTER, GRAF, ZOLTAN, GULYAS, TAMAS
• Format: Patent
• Language: Finnish
• Published: 15.01.1992
• Edition: 5
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to a process for producing sexual products suitable for natural or artificial fertilization from mammalia through controlling the activity of their sexual organs in their pre- and post-natal lives, during their infancy, puberty and mature state and, in a given case, to produce offsprings from them as well as to increase several times the production of sexual products to a level far above that typical of the life's performance of the species. According to the invention the mammalia are treated at least once and at most 60 times with a compound of general formula (I), Glp-His-Trp-Ser-Tyr-X1-X2-X3-Pro-X4, (I) wherein X1 means a glycil-group or any other natural or synthetic D-aminoacid group, X2 means an L-aminoacid-group with a side chain of an alkyl-, phenyl, or triptophyl group containing 1-4 carbon atoms, X3 means an L-aminoacid group having a side chain of an alkyl group with 1-4 carbon atoms or an alkanoyl-amide group of 2-4 carbon atoms and X4 means a glycil-amide or an alkylamide group of 1-4 carbon atoms, or a salt or metal complex thereof in a dose of 0.01 to 500 mu g/body weight kg (bwkg), preferably 1 to 100 mu g/bwkg, wherein intervals of at least two hours and at most 7 days, preferably 2 to 8 hours, are kept between the individual treatments.