GEMINALA DIHALOGENDERIVAT AV KONDENSERADE PYRIMIDIN-4-ON-FOERENINGAR FOERFARANDE FOER DERAS FRAMSTAELLNING OCH FARMACEUTISKA KOMPOSITIONER INNEHAOLLANDE DESSA

Geminal dihalogen derivatives of condensed pyrimidine-4-one compounds of the general formula [wherein R represents hydrogen, lower alkyl, or lower alkoxycarbonyl; R represents hydrogen, lower alkyl, ester group, carboxy or a derivative thereof, cyano, phenyl or halogen; R represents hydrogen, lower...

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Main Authors HORVATH AGNES, BREINING TIBOR, HERMECZ ISTVAN, KOEKOESI JOZSEF, MESZAROS ZOLTAN, BITTER ISTVAN, VASVARI (DEBRECZY) LELLE
Format Patent
LanguageFinnish
Published 12.11.1980
Edition3
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Summary:Geminal dihalogen derivatives of condensed pyrimidine-4-one compounds of the general formula [wherein R represents hydrogen, lower alkyl, or lower alkoxycarbonyl; R represents hydrogen, lower alkyl, ester group, carboxy or a derivative thereof, cyano, phenyl or halogen; R represents hydrogen, lower alkyl or phenyl; X represents halogen; n is the integer 0, 1 or 2] and the salts and optically active antipodes thereof are of interest as chemical intermediates; some also exhibit a variety of physiological activities and may be formulated into pharmaceutical compositions in conventional manner. The novel compounds can be made by halogenating a corresponding starting material wherein one or both X-substituents are hydrogen.
Bibliography:Application Number: FI19800001512