FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA RACEMISKA OCH OPTISKT AKTIVA SEMIPROSTANOIDGLYKOSIDER OCH -TIOGLYKOSIDER

Racemic or optically active compounds with antitumor activity of the formula: wherein X is oxygen or sulfur; R1 is hydrogen, C1 to C4 alkanoyl, benzoyl or phenyl-substituted benzoyl; R2 is hydrogen or C1 to C4 alkanoyl; R3 is C2 to C40 straight or branched chain alkyl substituted by hydroxy, epoxy,...

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Bibliographic Details
Main Authors STADLER ISTVAN, KOSZEGI BELA, KOVACS GABOR, INSTITORIS LASZLO, DALMADI GYULA, SZABO TIBOR
Format Patent
LanguageFinnish
Published 10.02.1986
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Racemic or optically active compounds with antitumor activity of the formula: wherein X is oxygen or sulfur; R1 is hydrogen, C1 to C4 alkanoyl, benzoyl or phenyl-substituted benzoyl; R2 is hydrogen or C1 to C4 alkanoyl; R3 is C2 to C40 straight or branched chain alkyl substituted by hydroxy, epoxy, amino, C1 to C6 alkylamino, C1 to C6 dialkylamino, C1 to C6 alkanoyloxy or, C1 to C4 alkoxycarbonyl; cyclohexyl, phenyl unsubstituted or substituted by halogen, amino, C1 to C4 alkyl-substituted amino, C1 to C4 alkoxy, nitro, or hydroxy; C1 to C6 alkanoyl; allyl or phenyl-C1 to C4 alkyl unsubstituted or substituted by a C2 to C6 alkene group; or where X is sulfur R3 is as defined above or is C1 to C40 straight or branched chain alkyl; and DIFFERENCE represents the exo- or endo-steric position in the ring and indicates an alpha - or beta -steric position in the side chain are disclosed.
Bibliography:Application Number: FI19780002913