FOERFARANDE FOER FRAMSTAELLNING AV TERAPEUTISKT ANVAENDBARA 4,-DIMETYL-4-SILA-FETTSYRAAMIDER

Novel compounds of the formula in which each of R1, R2 and R3 are independently alkyl, and R is an optionally substituted aralkyl, phenyl, indolyl or benzocycloalkyl radical. They are prepared by acylating a corresponding compound of formula H2N-R with a corresponding compound or a reactive derivati...

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Bibliographic Details
Main Author BARCZA SANDOR
Format Patent
LanguageFinnish
Published 29.06.1984
Edition3
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:Novel compounds of the formula in which each of R1, R2 and R3 are independently alkyl, and R is an optionally substituted aralkyl, phenyl, indolyl or benzocycloalkyl radical. They are prepared by acylating a corresponding compound of formula H2N-R with a corresponding compound or a reactive derivative thereof. The 4-sila carboxylic acids are novel and are prepared in via intermediates of which several are novel and in which the carboxylic radical is replaced by a methylol resp. a boron containing methylene group. The compounds I are useful as anti-atherosclerotic agents.
Bibliography:Application Number: FI19790003333