METHOD OF DETERMINING MMP-8 ACTIVATION

The present invention relates to a novel MMP-8 middle-part activation product. The invention also relates to detecting such a MMP-8 middle-part activation product or activated MMP-8 fragments in a biological sample derived from a subject and to the use thereof for diagnosing diseases which relate to...

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Bibliographic Details
Main Authors RÅMAN, Ismo, KORVUO, Armi, GIESELMANN, Dirk-Rolf, SORSA, Timo, MAIER, Kurt, MÄNTYLÄ, Päivi, TIISALA, Sinikka
Format Patent
LanguageEnglish
Finnish
Swedish
Published 31.05.2019
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Summary:The present invention relates to a novel MMP-8 middle-part activation product. The invention also relates to detecting such a MMP-8 middle-part activation product or activated MMP-8 fragments in a biological sample derived from a subject and to the use thereof for diagnosing diseases which relate to abnormal or elevated levels of activated MMP-8. Esillä olevan keksinnön kohteena on uusi MMP-8-keskiosan aktivointituote. Keksinnön kohteena on myös tällaisen MMP-8-keskiosan aktivointituotteen tai aktivoituneiden MMP-8-fragmenttien ilmaiseminen kohteesta saadusta biologisesta näytteestä sekä sen käyttö aktivoituneen MMP-8:n epänormaaleihin tai kohonneisiin tasoihin liittyvien sairauksien diagnosointiin.
Bibliography:Application Number: FI20140005192