2-(5-FLUORO-1-(2-FLUOROBENZYL)-1H-PYRAZOLO[3,4-b]PYRIDIN-3-IL)-5-NITROSOPYRIMIDIN-4,6-DIAMINE OR A SALT THEREOF, PROCEDURE FOR ITS PREPARATION AND ITS USE IN THE SYNTHESIS OF VERICIGUAT (Machine-translation by Google Translate, not legally binding)

• Main Authors: DOBARRO RODRIGUEZ, Alicia, SANCHEZ CASALS, Carles, GONZALEZ GARCIA, Jordi
• Format: Patent
• Language: English; Spanish
• Published: 12.12.2023
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-nitrosopyrimidin-4,6-diamine or a salt of the same, procedure for its preparation and its use in the synthesis of vericiguat. The present invention relates to a new intermediate useful in the synthesis of vericiguat, to a process for obtaining it, to the use of said intermediate for the preparation of vericiguat and to a process for the preparation of vericiguat that makes use of said intermediate. (Machine-translation by Google Translate, not legally binding) 2-(5-fluoro-1-(2-fluorobencil)-1H-pirazolo[3,4-b]piridin-3-il)-5-nitrosopirimidin-4,6-diamina o una sal de la misma, procedimiento para su preparación y su uso en la síntesis de vericiguat. La presente invención se refiere a un nuevo intermedio útil en la síntesis de vericiguat, a un procedimiento para su obtención, al uso de dicho intermedio para la preparación de vericiguat y a un procedimiento para la preparación de vericiguat que hace uso de dicho intermedio.