Endoprótesis de elución de fármaco con una capa de liberación biodegradable fijada con un recubrimiento de imprimación electroinjertado

• Main Authors: Bureau, Christophe, Haroun, Férial, Henault, Elodie
• Format: Patent
• Language: Spanish
• Published: 31.10.2022
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PROSTHESES; TREATMENT OR PROTECTION OF EYES OR EARS

Se describe un fármaco que eluye para prevenir la restenosis, evitar la trombosis y permitir la proliferación y migración tempranas de las células endoteliales. El stent tiene una superficie con una capa que promueve la proliferación y adhesión de las células endoteliales y un revestimiento de polímero biodegradable que alberga el fármaco que cubre la superficie que se degrada para liberar completamente el fármaco. (Traducción automática con Google Translate, sin valor legal) A drug eluting preventing restenosis, avoiding thrombosis and allowing for early proliferation and migration of endothelial cells is disclosed. The stent has a surface with a layer that promotes proliferation and adhesion of the endothelial cells and a drug hosting biodegradable polymer coating covering the surface which is degraded to completely release the drug.