NEW WATER SOLUBLE BODIPY DYES THROUGH SIMPLE FUNCTIONALIZATION IN BORON (Machine-translation by Google Translate, not legally binding)

• Main Authors: Bañuelos Prieto, Jorge, Schad Alburquerque, Cristóbal Martín, Lora Maroto, Beatriz, Ray Leiva, César, Díaz Norambuena, Carolina, Moreno Jimenez, Florencio, De la Moya Cerero, Santiago
• Format: Patent
• Language: English; Spanish
• Published: 03.10.2022
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; ADHESIVES; AUXILIARY PROCESSES IN PHOTOGRAPHY; CHEMISTRY; CINEMATOGRAPHY; DYES; ELECTROGRAPHY; HOLOGRAPHY; LAKES; MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE; METALLURGY; MISCELLANEOUS APPLICATIONS OF MATERIALS; MISCELLANEOUS COMPOSITIONS; MORDANTS; NATURAL RESINS; ORGANIC CHEMISTRY; ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES; PAINTS; PHOTOGRAPHIC PROCESSES, e.g. CINE, X-RAY, COLOUR,STEREO-PHOTOGRAPHIC PROCESSES; PHOTOGRAPHY; PHOTOSENSITIVE MATERIALS FOR PHOTOGRAPHIC PURPOSES; PHYSICS; POLISHES

New water-soluble BODIPY dyes by simple boron functionalization. The known hydrophobicity of BODIPYs and their most common analogs constitutes an important limitation to their optimal use in some applications that require solubility in water, for which it is of interest to obtain BODIPYs soluble in water or highly hydrophilic media from precursor BODIPYs. conventional. The invention refers to the structural design, synthetic access and solubility in water of a new group of hydrophilic molecular dyes belonging to the BODIPYs family, which present as advantages the generality and ease of obtaining them from conventional BODIPY dyes (based on F-BODIPY), this preparation implying the minimum disturbance of the photophysical properties of the starting dye, as well as a significant chemical and photophysical robustness, which implies its potential use in photonic, physical and chemical applications in aqueous or highly hydrophilic media. (Machine-translation by Google Translate, not legally binding) Nuevos colorantes BODIPY solubles en agua mediante funcionalización sencilla en boro. La conocida hidrofobicidad de los BODIPYs y sus análogos más comunes constituye una limitación importante a su empleo óptimo en algunas aplicaciones que requieren solubilidad en agua, por lo que resulta de interés la obtención de BODIPYs solubles en agua o medios altamente hidrofílicos a partir de BODIPYs precursores convencionales. La invención se refiere el diseño estructural, acceso sintético y solubilidad en agua de un nuevo grupo de colorantes moleculares hidrofílicos pertenecientes a la familia de los BODIPYs, que presentan como ventajas la generalidad y facilidad de su obtención a partir de colorantes BODIPY convencionales (basados en F-BODIPY), implicando dicha preparación la mínima perturbación de las propiedades fotofísicas del colorante de partida, así como una significativa robustez química y fotofísica, lo cual implica su potencial uso en aplicaciones fotónicas, físicas y químicas en medios acuosos o altamente hidrofílicos.