Procedimiento para producir (4S)-4-[4-ciano-2-(metilsulfonil)fenil]-3,6-dimetil-2-oxo-1-[3-(trifluorometil)fenil]-1,2,3,4-tetrahidropirimidin-5-carbonitrilo

Compuesto de fórmula (I) **(Ver fórmula)** en la forma cristalina (A), caracterizado porque el diagrama de difracción de rayos X del compuesto muestra máximos de pico del ángulo 2 Theta a 7,5, 12,4, 15,1, 18,5, 18,7, 22,9, 24,7 y 26,5. The invention relates to a new and improved method for preparati...

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Bibliographic Details
Main Authors OLENIK, Britta, KEIL, Birgit, RUBENBAUER, Philipp, SCHIRMER, Heiko
Format Patent
LanguageSpanish
Published 17.11.2021
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compuesto de fórmula (I) **(Ver fórmula)** en la forma cristalina (A), caracterizado porque el diagrama de difracción de rayos X del compuesto muestra máximos de pico del ángulo 2 Theta a 7,5, 12,4, 15,1, 18,5, 18,7, 22,9, 24,7 y 26,5. The invention relates to a new and improved method for preparation of (4S)-4-[4-cyano-2-(methyl sulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile of formula (I), as well as the preparation and use of the crystal form (A) of (4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro pyrimidine-5-carbonitrile of formula (I).
Bibliography:Application Number: ES20160713747T