Quinazolinonas como inhibidores de fosfatidilinositol 3-quinasa delta humano

Una composición farmacéutica que comprende el compuesto **(Ver fórmula)** o una sal farmacéuticamente aceptable del mismo. Compounds that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isof...

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Bibliographic Details
Main Authors HUANG, Danwen, OOI, Hua Chee, RUAN, Fuqiang, FOWLER, Kerry W, OLIVER, Amy R, KESICKI, Edward A, PURI, Kamal Deep, TREIBERG, Jennifer
Format Patent
LanguageSpanish
Published 04.11.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Una composición farmacéutica que comprende el compuesto **(Ver fórmula)** o una sal farmacéuticamente aceptable del mismo. Compounds that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which PI3Kδ plays a role in leukocyte function, using the compounds also are disclosed.
Bibliography:Application Number: ES20160185213T