Activación específica de una célula T reguladora y su uso para el tratamiento del asma, enfermedades alérgicas, enfermedades autoinmunes, rechazo de injertos y para la inducción de tolerancia

The present invention relates to a Treg cell activator for regulatory (Treg) cell activation via interaction with a Treg cell epitope as set forth in SEQ ID NO:1 which is HIV-1 gp120, or HIV-1 gp120 derived fragments, peptides or polypeptides thereof comprising an amino acid sequence as set forth in...

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Bibliographic Details
Main Authors SCHNEIDER, Franz-Josef, SCHMITT, Edgar, BECKER, Christian, JONULEIT, Helmut, BOPP, Tobias
Format Patent
LanguageSpanish
Published 17.05.2021
Subjects
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
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Summary:The present invention relates to a Treg cell activator for regulatory (Treg) cell activation via interaction with a Treg cell epitope as set forth in SEQ ID NO:1 which is HIV-1 gp120, or HIV-1 gp120 derived fragments, peptides or polypeptides thereof comprising an amino acid sequence as set forth in SEQ ID NO.: 3, SEQ ID NO.: 4, SEQ ID NO.: 5, SEQ ID NO.: 6, SEQ ID NO.: 7, SEQ ID NO.: 8, SEQ ID NO.: 9, or SEQ ID NO.: 10 for use in a method for the prevention or treatment of a disease, which is characterized in that its clinical picture is influenced positively by an increase of activated Treg cells in response to the Treg cell activator.
Bibliography:Application Number: ES20160166807T