Combinación de un conjugado de naloxol-peg y un agonista opioide

Naloxol-polyethylene glycol conjugates of the formula: are provided in oxalate or phoshate salt forms including crystalline forms. To achieve a central analgesic effect, the conjugates will be administered an opioid agonist.

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Bibliographic Details
Main Authors AURELL, Carl-Johan, SEBHATU, Tesfai, PARENT, Stephan, ASLUND, Bengt Leonard, JENSEN, David Richard, LECHUGA-BALLESTEROS, David, YMEN, Bo Ingvar, BOHLIN, Martin Hans, HEALY, Eric Thomas, JONAITIS, David Thomas
Format Patent
LanguageSpanish
Published 26.05.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Naloxol-polyethylene glycol conjugates of the formula: are provided in oxalate or phoshate salt forms including crystalline forms. To achieve a central analgesic effect, the conjugates will be administered an opioid agonist.
Bibliography:Application Number: ES20150188944T