Proceso para la preparación de un complejo de gadobenato dimeglumina en forma sólida

Un proceso para la preparación de una forma sólida de un compuesto gadobenato dimeglumina,de fórmula (1):**Fórmula** comprendiendo el secado por pulverización de una composición líquida de dicho compuesto. The present invention discloses a process for the preparation of gadobenate dimeglumine comple...

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Main Authors ANELLI, PIER LUCIO, MOROSINI, PIER FRANCESCO, UGGERI, FULVIO, FERRIGATO, AURELIA, FRETTA, ROBERTA, LATTUADA, LUCIANO, CERAGIOLI, SILVIA
Format Patent
LanguageSpanish
Published 22.10.2013
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Un proceso para la preparación de una forma sólida de un compuesto gadobenato dimeglumina,de fórmula (1):**Fórmula** comprendiendo el secado por pulverización de una composición líquida de dicho compuesto. The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently obtained by spray-drying a corresponding liquid suspension at a given temperature and concentration. The present invention is particularly advantageous for the industrial scale as the solid form may be obtained by employing water as a solvent, which is a non-toxic solvent, easy to handle and basically not requiring troublesome health or safety precautions.
Bibliography:Application Number: ES20100781898T