QTL para resistencia a mastitis en ganado bovino

• Main Authors: SCHULMAN, NINA FREDERIKA, SOERENSEN, PETER, ISO-TOURU, TERHI KATARLINA, VIITALA, SIRJA MARIA, HASTINGS, NICOLA, MAJGREN, BENTE FLUEGEL, ANDERSSON-EKLUND, INGRID LENA, WILLIAMS, JOHN LEWIS WILLIAM, SVENDSEN, SOEREN, VILKKI, HELMI JOHANNA, BENDIXEN, CHRISTIAN, WOOLLIAMS, JOHN ARTHUR, VIINALASS, HALDJA, THOMSEN, BO, FERNANDEZ AVILA, ANA ISABEL, SABRY, AYMAN MAHMOUD, SAHANA, GOUTAM, LUND, MOGENS SANDOE, VAARV, SIRJE
• Format: Patent
• Language: Spanish
• Published: 11.10.2013
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

Método para determinar la resistencia frente a mastitis en cualquier sujeto bovino de las razas de RojaDanesa, Ayrshire, Roja y Blanca Sueca y Holstein, que comprende detectar en una muestra de dicho sujetobovino la presencia o ausencia de al menos un marcador genético que está ligado con al menos un rasgoindicativo de resistencia a mastitis, en el que dicho al menos un marcador genético está ubicado en elcromosoma bovino BTA9 en la región flanqueada por y que incluye los marcadores microsatélitespolimórficos C6orf93 e inra084, en el que la presencia o ausencia de dicho al menos un marcador genéticoes indicativo de resistencia a mastitis de dicho sujeto bovino o descendencia del mismo. The invention relates to a method for determining mastitis resistance in bovine subjects, wherein mastitis resistance comprise resistance to both sub-clinical and clinical mastitis. In particular, the method of the invention involves identification of genetic markers and/or Quantitative Trait Locus (QTL) for the determination of mastitis resistance in a bovine subject. The determination of mastitis resistance involves resolution of the specific microsatellite status. Furthermore, the invention relates to a diagnostic kit for detection of genetic marker(s) associated with mastitis resistance. The method and kit of the present invention can be applied for selection of bovine subjects for breeding purposes. Thus, the invention provides a method of genetically selecting bovine subjects with mastitis resistance, thereby yielding cows less prone to mastitis.