Co-cristales de duloxetina y naproxeno

Un co-cristal que comprende duloxetina, bien como una base libre o como su sal fisiológicamente aceptable, y almenos un formador de co-cristal, que es (S)-naproxeno, o sus sales, en el que la relación molecular entre la duloxetinay el (S)-naproxeno es 2:3. The present invention relates to co-crystal...

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Bibliographic Details
Main Authors RAMIREZ ARTERO, JESUS, CERON BERTRAN, JORDI CARLES, BENET BUCHHOLZ, JORDI, BUSCHMANN, HELMUT, SOLA CARANDELL, LLUIS
Format Patent
LanguageSpanish
Published 21.06.2013
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Un co-cristal que comprende duloxetina, bien como una base libre o como su sal fisiológicamente aceptable, y almenos un formador de co-cristal, que es (S)-naproxeno, o sus sales, en el que la relación molecular entre la duloxetinay el (S)-naproxeno es 2:3. The present invention relates to co-crystals of duloxetine and co-crystal formers selected from active agents preferably with analgesic activity, processes for preparation of the same and their uses as medicaments or in pharmaceutical formulations, more particularly for the treatment of pain.
Bibliography:Application Number: ES20090749634T