Anticuerpos optimizados que seleccionan como diana CD19

The present disclosure describes antibodies that target CD19, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an Fcg³R or alters effector function as compared to the parent antibody. Also disclosed are methods of us...

Full description

Saved in:
Bibliographic Details
Main Authors Bernett, Matthew J, Richards, John O, Zhukovsky, Eugene Alexander, Lazar, Gregory Alan, Karki, Sher Bahadur, Pong, Erik WeiKing, Desjarlais, John R, Chu, Seung Yup
Format Patent
LanguageSpanish
Published 13.07.2022
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:The present disclosure describes antibodies that target CD19, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an Fcg³R or alters effector function as compared to the parent antibody. Also disclosed are methods of using said antibodies.
Bibliography:Application Number: ES20110173336T