Procedimientos de producción de ácido succínico

• Main Authors: CALANDE, OLIVIER, VARLAMOFF, CAROLINE, SEGUEILHA, LAURENT, DEHAY, FREDERIC
• Format: Patent
• Language: Spanish
• Published: 23.11.2012
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PROCESSES USING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Procedimiento de producción de ácido succínico y/o de iones succinato por fermentación en condicionesanaerobias de una cepa de Escherichia coli, que comprende:(A) una etapa de fermentación de una fuente de carbono en un fermentador, con aporte de CO2, realizadacon los conductos de ventilación del fermentador cerrados de manera que el aporte de CO2 esté sometidoal consumo de CO2 por la cepa; seguida, antes del agotamiento total de la fuente de carbono, de(B) una etapa de fermentación de la fuente de carbono restante, sin aporte de CO2, a fin de consumir elCO2 residual. Producing succinic acid by anaerobic fermentation of a carbon source with an Escherichia colistrain comprises a first stage in which carbon dioxide is supplied in an amount dependent on its consumption by the strain and, before total exhaustion of the carbon source, a second step in which the remaining carbon source is fermented without supplying carbon dioxide so as to consume residual carbon dioxide. An independent claim is also included for producing succinic acid by anaerobic fermentation with an Escherichia colistrain in the presence of carbon dioxide while adding a magnesium compound to the fermentation medium to adjust the pH, where the resulting magnesium succinate is then converted to succinic acid.