CEMENTO DE FOSFATO CALCICO-SILICATO CALCICO PARA APLICACIONES BIOMEDICAS

• Main Authors: HAMDAN ALI ALKHRAISAT, MOHAMMAD, LOPEZ CABARCOS, ENRIQUE
• Format: Patent
• Language: Spanish
• Published: 17.07.2012
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PROSTHESES; TREATMENT OR PROTECTION OF EYES OR EARS

The present invention relates to a calcium phosphate/calcium silicate cement that comprises a 10 to 90% by volume fraction of silicon-doped brushite (DCPD, CaHPO4.2H2O), a hydrated calcium silicate fraction (C-S-H) and a further fraction comprising hydroxyapatite. In addition, the invention relates to a method for preparing said cement and to the composite ceramic comprising beta tricalcium phosphate (Ca3(PO4)2) doped with silicon and silicocarnotite (Ca5(PO4)2SiO4), which is the result of the first step in said method. The present invention also relates to the use of matrices that include the cement or the ceramic in the preparation of therapeutic agents for maxillofacial and oral surgery, orthopaedic applications and/or controlled release of drugs, and also in tissue and bone engineering as cell-growth substrate.