Compuestos de pirido (2, 3-D) piridinona y sus uso como inhibidores de PI3

The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-Kalpha).

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Bibliographic Details
Main Authors KANIA, ROBERT STEVEN, PLEWE, MICHAEL BRUNO, DRESS, KLAUS RUPRECHT, BHUMRALKAR, DILIP, HOFFMAN, JACQUI ELIZABET, LE, PHUONG THI QUY, CHENG, HENGMIAO, TRAN, KHANH TUAN, JOHNSON, MARY CATHERINE, NAMBU, MITCHELL DAVID, PAIRISH, MASON ALAN
Format Patent
LanguageSpanish
Published 26.03.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-Kalpha).
Bibliography:Application Number: ES20070804890T