BIOSINTESIS DE DERIVADOS DE MONACOLINA J
The invention relates to a process for obtaining monacolin J derivatives (I), wherein R 1 is COR 2 , wherein R 2 is selected from C1-C15 alkyl, C3-C15 cycloalkyl, C2-C15 alkenyl, C2-C15 alkynyl, aryl and heterocyclyl; which comprises producing monacolin J by fermentation from a monacolin J-producing...
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Main Authors | , , , |
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Format | Patent |
Language | Spanish |
Published |
10.06.2011
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Subjects | |
Online Access | Get full text |
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Summary: | The invention relates to a process for obtaining monacolin J derivatives (I), wherein R 1 is COR 2 , wherein R 2 is selected from C1-C15 alkyl, C3-C15 cycloalkyl, C2-C15 alkenyl, C2-C15 alkynyl, aryl and heterocyclyl; which comprises producing monacolin J by fermentation from a monacolin J-producing microorganism; and acylating the hydroxyl group present in the C8 position of the monacolin J previously obtained by means of adding a suitable acylating agent to the fermentation medium to obtain the desired monacolin J derivative (I). |
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Bibliography: | Application Number: ES20080002971 |