RESTAURACION DE LAS MOLECULAS HLA DE CLASE I MEDIANTE TERAPIA GENICA EMPLEANDO VECTORES ADENOVIRALES PORTANDO EL GEN DE LA BETA 2-MICROGLOBULINA

The invention relates to the recovery of the antigenic presentation capacity of tumors in vivo by means of. The restoration of the expression of hla class i molecules using adenoviral vectors. The same will be done in those tumors totally negative for the expression of hla class i molecules due to a...

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Bibliographic Details
Main Authors APTSIAURI NATALIA, GARRIDO TORRES-PUCHOL FEDERICO, DEL CAMPO ALONSO ANA BELEN, MENDEZ VALES ROSA, RUIZ-CABELLO OSUNA FRANCISCO
Format Patent
LanguageSpanish
Published 05.03.2010
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to the recovery of the antigenic presentation capacity of tumors in vivo by means of. The restoration of the expression of hla class i molecules using adenoviral vectors. The same will be done in those tumors totally negative for the expression of hla class i molecules due to alterations in the b2-microglobulin, implying the previous diagnosis of the alteration present in the tumor. (Machine-translation by Google Translate, not legally binding)
Bibliography:Application Number: ES20070001222