FORMULACION ESTABLE DE OXALIPLATINO

Una composición farmacéutica estable en el almacenamiento que comprende una solución de oxaliplatino en agua y un carbohidrato, en la que la cantidad de carbohidrato está en el intervalo de 0,0010% a 0,05% en p/v de la solución de oxaliplatino en agua. A storage stable pharmaceutical composition com...

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Main Authors SINGH, AJEET KUMAR, JAIN, DEEPTI, MUKHARJEE, RAMA, PANANCHUKUNNATH, MANOJ KUMAR, PARSHOTAMDAS, DEEPAK JUDGELAL, UPADHYAY, SATISH CHANDRA
Format Patent
LanguageSpanish
Published 01.02.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Una composición farmacéutica estable en el almacenamiento que comprende una solución de oxaliplatino en agua y un carbohidrato, en la que la cantidad de carbohidrato está en el intervalo de 0,0010% a 0,05% en p/v de la solución de oxaliplatino en agua. A storage stable pharmaceutical composition comprising a solution of Oxaliplatin in water and a catalytic amount of a carbohydrate. A process for forming such pharmaceutical composition comprising dissolving a known amount of Oxaliplatin in water; adding an amount of carbohydrate in the range of 0.0010 % to 0.05% w/v with respect to such solution; agitating the mixture to get clear solution; filtering it through a filter membrane under aseptic conditions; and filling the solution resulting into glass vials sealed with elastomeric stoppers and aluminium flip-off seals.
Bibliography:Application Number: ES20060254598T