ANTIMICROBIAL CYCLIC PEPTIDES

• Main Authors: MONTESINOS SEGUI EMILI, COLETTE MONROC SYLVIE MARTINE, BARDAJI RODRIGUEZ EDUARD, PLANAS GRABULEDA MARTA, FELIU SOLEY LIDIA, BADOSA ROMACHO ESTHER
• Format: Patent
• Language: English; Spanish
• Published: 16.09.2007
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; TRAPPING

The invention relates to novel cyclic peptides with antimicrobial properties. The inventive peptides contain an even number of between 4 and 10 amino acids and a have a molar lysine concentration of between 40 % and 60 %. The invention also relates to the synthesis and use of the aforementioned peptides as antimicrobial agents against bacterial and fungi that are pathogenic to plants. The invention further relates to compositions containing said peptides and an auxiliary agent and to a method for preventing and treating infections and diseases in plants caused by pathogenic bacteria and fungi. La presente invención se refiere a nuevos péptidos cíclicos que tienen propiedades antimicrobianas. Dichos péptidos tienen un número par de aminoácidos comprendido entre 4 y 10, y un contenido molar de lisina comprendido entre el 40% y el 60%. La invención describe la síntesis y la utilización de los mencionados péptidos como agentes antimicrobianos frente a bacterias y hongos patógenos para plantas. También se refiere a composiciones que comprenden dichos péptidos y un agente auxiliar, y a un método para prevenir y tratar infecciones y enfermedades de las plantas provocadas por bacterias y hongos patógenos.