DEPOSITO PARA FARMACOS DE PELICULA POLIMERICA DELGADA

• Main Authors: KLEINER, LOTHAR, W, GOLDMAN, ELI, J, PUDJIJANTO, STEPHANUS, VENKATRAMAN, SUBRAMANIAN, S
• Format: Patent
• Language: Spanish
• Published: 16.07.2005
• Edition: 7
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; BABY COMFORTERS; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; DEVICES FOR RECEIVING SPITTLE; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS; ELECTROTHERAPY; GENERAL PROCESSES OF COMPOUNDING; HUMAN NECESSITIES; HYGIENE; MAGNETOTHERAPY; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; RADIATION THERAPY; THEIR PREPARATION OR CHEMICAL WORKING-UP; ULTRASOUND THERAPY; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS; WORKING-UP

Depósito de fármacos de película delgada (24) para un dispositivo de administración de fármaco de electrotransporte que comprende un polímero hidrofílico hidratable, siendo dicha película capaz de formar un hidrogel cuando se pone en contacto con un líquido hidratante, presentando dicha película, cuando se hidrata sustancialmente a un 400% un módulo de corte G¿ de sustancialmente 1 a 100 kPa y en el que dicha película, cuando no está sustancialmente hidratada, es capaz de absorber por lo menos cuatro veces su peso en líquido hidratante dentro de un periodo de sustancialmente 30 minutos, caracterizado porque el polímero comprende hidroxipropilcelulosa o poliuretano. The present invention relates to hydratable drug reservoir films for electrotransport drug delivery devices and to electrotransport drug delivery systems containing the hydratable drug reservoirs and to methods for manufacturing and using such systems. The hydratable reservoir films according to this invention are easily manufacturable and rapidly imbibe water and/or drug solution with good water retention and stability.