Set of platinum (II) trans compounds combating tumours comprises halogen and amine ligand products as anticarcinogenic agents
The set of platinum (II) trans compounds combating tumours consists of agents of general formula PtX2L1>L2>, where X is a halogen and L1> and L2> are amine ligands. Thus the trans-(PtCl2(amine)(dimethylamine)) compounds have e.g. dimethylamine as L1>, and L2> is e.g. R-NH2 aliphati...
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Format | Patent |
Language | English Spanish |
Published |
01.09.2004
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Edition | 7 |
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Abstract | The set of platinum (II) trans compounds combating tumours consists of agents of general formula PtX2L1>L2>, where X is a halogen and L1> and L2> are amine ligands. Thus the trans-(PtCl2(amine)(dimethylamine)) compounds have e.g. dimethylamine as L1>, and L2> is e.g. R-NH2 aliphatic amines where R is an alkyl group. EMBODIMENT - The compounds are active against carcinogenic cells.
The set of platinum (II) trans compounds combating tumours consists of agents of general formula PtX2L1>L2>, where X is a halogen and L1> and L2> are amine ligands. Thus the trans-(PtCl2(amine)(dimethylamine)) compounds have e.g. dimethylamine as L1>, and L2> is e.g. R-NH2 aliphatic amines where R is an alkyl group. EMBODIMENT - The compounds are active against carcinogenic cells.
Compuestos trans de platino (II) de fórmula trans-[PtCl{sub,2} (amina) (dimetilamina)], con actividad antitumoral, con fórmula general PtX{sub,2}L{sup,1}L{sup,2} En esta fórmula X es un halógeno, preferentemente cloro y L{sup,1} y L{sup,2} son ligandos amina. De estos ligandos L{sup,1} es preferentemente dimetilamina y L{sup,2} son preferentemente aminas alifáticas R- NH{sub,2} en las que R es un grupo alquilo de cadena lineal o cíclina. Estos compuestos son activos frente a células cancerígenas. |
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AbstractList | The set of platinum (II) trans compounds combating tumours consists of agents of general formula PtX2L1>L2>, where X is a halogen and L1> and L2> are amine ligands. Thus the trans-(PtCl2(amine)(dimethylamine)) compounds have e.g. dimethylamine as L1>, and L2> is e.g. R-NH2 aliphatic amines where R is an alkyl group. EMBODIMENT - The compounds are active against carcinogenic cells.
The set of platinum (II) trans compounds combating tumours consists of agents of general formula PtX2L1>L2>, where X is a halogen and L1> and L2> are amine ligands. Thus the trans-(PtCl2(amine)(dimethylamine)) compounds have e.g. dimethylamine as L1>, and L2> is e.g. R-NH2 aliphatic amines where R is an alkyl group. EMBODIMENT - The compounds are active against carcinogenic cells.
Compuestos trans de platino (II) de fórmula trans-[PtCl{sub,2} (amina) (dimetilamina)], con actividad antitumoral, con fórmula general PtX{sub,2}L{sup,1}L{sup,2} En esta fórmula X es un halógeno, preferentemente cloro y L{sup,1} y L{sup,2} son ligandos amina. De estos ligandos L{sup,1} es preferentemente dimetilamina y L{sup,2} son preferentemente aminas alifáticas R- NH{sub,2} en las que R es un grupo alquilo de cadena lineal o cíclina. Estos compuestos son activos frente a células cancerígenas. |
Author | NAVARRO RANNINGER CARMEN GONZALEZ VADILLO ANA M |
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DocumentTitleAlternate | COMPUESTOS TRANS DE PLATINO (II) DE FORMULA TRANS- (PTCL2 (AMINA) ( DIMETILAMINA)), CON ACTIVIDAD ANTITUMORAL. |
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SubjectTerms | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
Title | Set of platinum (II) trans compounds combating tumours comprises halogen and amine ligand products as anticarcinogenic agents |
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