PROCEDIMIENTO MEJORADO PARA LA OBTENCION DE ESTERES DEL ACIDO 2-ACETIL-CARBOXILICO

• Main Authors: EICHBERGER, GUNTER, BURSCHIK, GERHARD, POSCHKO, HARALD, HUBER, WOLFGANG
• Format: Patent
• Language: Spanish
• Published: 16.12.2001
• Edition: 7
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; APPARATUS THEREFOR; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; THEIR RELEVANT APPARATUS; TRANSPORTING

PROCEDIMIENTO PARA LA OBTENCION DEL ESTER DEL ACIDO 2 ACETILCARBOXILICO MEDIANTE LA REACCION DE UN ESTER DE ACIDO ACETICO CON 1 A 6 ATOMOS DE C EN LA PARTE DEL ALQUILO CON UN ALDEHIDO ALIFATICO CON 1 A 12 ATOMOS DE C EN PRESENCIA DE UN CATALIZADOR DE CONDENSACION A 0 HASTA 40 °C, A CONTINUACION SE QUITA EL AGUA FORMADA EN LA REACCION Y LOS PRODUCTOS QUE NO HAN REACCIONADO, Y SE HIDROGENAN A 20 - 160 °C ESTANDO EN LA PRIMERA FASE DE LA HIDROGENACION A UNA TEMPERATURA ENTRE 20 Y 90 °C, Y EN LA SEGUNDA FASE LA TEMPERATURA, SEGUN SEA LA TEMPERATURA DE PARTIDA, DE 50 HASTA 160 °C. Preparation of 2-acetylcarboxylic acid esters (I) comprises condensation of an acetic acid ester with an aldehyde, followed by removal of any unreacted educts and water formed during condensation and hydrogenation of the resulting intermediate. Preparation of 2-acetylcarboxylic acid esters (I) comprises reacting an acetic acid ester with an aldehyde, followed by hydrogenation. The novelty comprises four factors: (1) During the first stage, the use of acetic acid 1-6C alkyl esters and 1-12C aldehydes, in the presence of a condensation catalyst at 0-40 degrees C; (2) Removal of any unreacted educt and any water produced after the condensation has taken place; (3) Hydrogenation of the residue in the presence of a catalyst at 20-160 degrees C and 1-100 bar, where the hydrogenation is divided into two stages, with the first stage taking place at 20-90 degrees C and the second at 50-160 C; and (4) Isolation of (I) by distillation.