COMPOSICIONES POLIMERAS Y DISPOSITIVO PARA OCLUIR CANALES EN MAMIFEROS VIVOS

• Main Author: SCHMITT, EDWARD, E
• Format: Patent
• Language: Spanish
• Published: 16.02.2000
• Edition: 7
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DIAGNOSIS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; IDENTIFICATION; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PROSTHESES; SURGERY; TREATMENT OR PROTECTION OF EYES OR EARS

LOS METODOS PARA OCLUSION DE CONDUCTOS EN MAMIFEROS VIVOS EMPLEAN COMPOSICIONES POLIMERICAS TERMOPLASTICAS QUE FUSIONAN JUSTO ENCIMA DE LAS TEMPERATURAS CORPORALES NORMALES. LA COMPOSICION FUNDIDA SE INYECTA EN EL CONDUCTO Y SOLIDIFICA IN SITU. LAS COMPOSICIONES PREFERIDAS CONTIENEN POLIMEROS CRISTALIZABLES DE CADENA LATERAL (SCC), EN PARTICULAR ELASTOMEROS TERMOPLASTICOS QUE CONTIENEN BLOQUES FIRMES DE SCC, CON FUSION A 34-45 C. SE ILUSTRA UN DISPOSITIVO DE INYECCION PARA EMPLEO EN EL METODO QUE CONTIENE UN DEPOSITO PARA LA COMPOSICION DE OCLUSION, UN CALENTADOR ELECTRICO PARA CALENTAR LA COMPOSICION, UN INYECTOR Y UN EMBOLO PARA EXTRUIR LA COMPOSICION FUNDIDA A TRAVES DEL INYECTOR. EL INVENTO ES PARTICULARMENTE UTIL PARA BLOQUEO DE CONDUCTOS LACRIMOGENOS EN EL TRATAMIENTO DEL SINDROME DE OJOS SECOS. A method of blocking channels in a mammal which channels normally carry a material from one point to another is carried out by injecting a heated flowable polymer into the channel and allowing the polymer to cool and solidify, thus creating a plug or channel occluder. The plug can be later removed physically in its solid form or removed gradually by softening and/or fluidizing it by heating and/or chemical means. The channel occluder is preferably comprised of a main chain or side-chain crystallizable polymer but may be comprised of other polymers provided the polymers are formulated to have certain characteristics. The polymers must be solid and/or non-flowable at body temperature or lower and flowable when heated slightly above body temperature, i.e., 10 centigrade degrees or less above body temperature. The polymer is capable of changing quickly from a flowable state to a non-flowable state by moving through only a few centigrade degrees of temperature and is a non-immunogenic, biocompatible material. Typical channels which may be reversibly occluded via the present invention include the vas deferens, the mature sperm excretory channel of the testis; the fallopian tube or oviduct, the viaduct conveying the ovum from the ovary to the uterus; the canaliculus lacrimalis, the passageway that allows excess tears to flow from the puncta of the eye to the lacrimal sac; and the cavity of the femoral shaft to fix the stem of replacement hip joint (ball and neck).