DISPOSITIVO Y PROCEDIMIENTO PARA LA SINTESIS DE MACROMOLECULAS

• Main Authors: BADER, RAOUL, HINZ, MICHAEL, SELIGER, HARTMUT
• Format: Patent
• Language: Spanish
• Published: 16.12.1999
• Edition: 6
• Subjects: CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; COMBINATORIAL CHEMISTRY; COMPOSITIONS BASED THEREON; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS; METALLURGY; ORGANIC CHEMISTRY; ORGANIC MACROMOLECULAR COMPOUNDS; PEPTIDES; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; THEIR PREPARATION OR CHEMICAL WORKING-UP; THEIR RELEVANT APPARATUS; TRANSPORTING

LA INVENCION TRATA DE UN DISPOSITIVO Y UN PROCEDIMIENTO PARA SINTETIZAR MACROMOLECULAS EN EL QUE ESTA PREVISTO CONDUCIR SOLUCIONES REACTIVAS A TRAVES DE UNOS CANALES DE REACCION (15), ORIENTADOS PREFERIBLEMENTE EN PARALELO A OTROS, Y CONECTADOS ENTRE SI POR CANALES INTERMEDIOS (16, 17), A CUYO EFECTO ENTRE CADA UNO DE LOS PASOS DE LA SINTESIS, LOS CANALES DE REACCION (15), EN LO TOCANTE AL MATERIAL PORTADOR (3) CARGADO CON LA SOLUCION REACTIVA, ESTAN DESPLAZADOS DE TAL MANERA QUE EN LA NUEVA POSICION LOS CANALES DE REACCION (15) CUBREN OTRAS ZONAS DE SINTESIS DISTINTAS A LAS QUE CUBRIAN EN LA POSICION ANTERIOR. DE ESTE MODO SE CONSIGUE LA SINTESIS DE UN GRAN NUMERO DE SECUENCIAS DIFERENTES CON UNA CANTIDAD DE PASOS DE SINTESIS A DAR RELATIVAMENTE PEQUEÑO. PCT No. PCT/EP97/00236 Sec. 371 Date Aug. 21, 1998 Sec. 102(e) Date Aug. 21, 1998 PCT Filed Jan. 20, 1997 PCT Pub. No. WO97/26986 PCT Pub. Date Jul. 31, 1997Provision is made, in a device and a process for the synthesis of macromolecules, for reagent solutions to be conveyed through reaction channels (15) which are connected to one another by intermediate channels (16, 17) and are preferably aligned parallel to one another, the reaction channels (15) being so displaced between individual synthesis steps relative to the carrier material acted on by the reagent solutions that, in the new position, the reaction channels (15) cover different synthesis zones from those in the previous position. In that manner provision is made for the synthesis of a large number of different sequences by relatively few synthesis steps.