Angiotensin II antagonists

Angiotensin II antagonists. The invention provides compounds of formula (I) which antagonize compounds angiotensin II at the body's receptor sites. It also provides pharmaceutical formulations which comprise a compound of formula I together with one or more pharmaceutically acceptable excipient...

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Main Authors WHITESITT CELIA ANN, PALKOWITZ ALAN DAVID, HAUSER KENNETH LEE, REEL JON KEVIN, LIFER SHERRYL LYNN, MARSHALL WINSTON STANLEY, STEINBERG MITCHELL IRVIN, SIMON RICHARD LEE, TAKEUCHI KUMIKO, THRASHER KENNETH JEFF, PFEIFER WILLIAM, BOYD DONALD BRADFORD
Format Patent
LanguageEnglish
Spanish
Published 16.10.1995
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Angiotensin II antagonists. The invention provides compounds of formula (I) which antagonize compounds angiotensin II at the body's receptor sites. It also provides pharmaceutical formulations which comprise a compound of formula I together with one or more pharmaceutically acceptable excipients, vehicles or diluents. It has application in the treatment of hypertension, congestive heart failure, kidney failure and glaucoma, and in the improvement of cognitive performance. ANTAGONISTAS DE ANGIOTENSINA II. LA INVENCION PROPORCIONA COMPUESTOS DE FORMULA (I) QUE ANTAGONIZA LA ANGIOTENSINA II EN LOS SITIOS RECEPTORES DEL CUERPO. TAMBIEN PROPORCIONA FORMULACIONES FARMACEUTICAS QUE COMPRENDEN UN COMPUESTO DE FORMULA I JUNTO CON UNO O MAS EXCIPIENTES ACEPTABLES FAMACEUTICAMENTE, VEHICULOS O DILUYENTES. TIENE APLICACION EN EL TRATAMIENTO DE LA HIPERTENSION, FALLO CARDIACO CONGESTIVO, INSUFICIENCIAS RENALES Y GLAUCOMA, ASI COMO EN LA MEJORA DEL RENDIMIENTO COGNITIVO.
Bibliography:Application Number: ES19930001321