METHODS FOR IMAGING USING SPCCT

The present invention relates to a method for imaging an anatomical structure in a subject in need thereof, comprising the following steps: a) providing an injectable pharmaceutical composition comprising, as a contrast agent, at least one nanoparticle having a mean hydrodynamic diameter below 10 nm...

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Bibliographic Details
Main Authors BOUSSEL, Loïc, LE DUC, Géraldine, TILLEMENT, Olivier, SI-MOHAMED, Salim, DOUEK, Philippe, LUX, François
Format Patent
LanguageEnglish
French
German
Published 27.08.2025
Subjects
HUMAN NECESSITIES
HYGIENE
MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES
MEDICAL OR VETERINARY SCIENCE
NANOTECHNOLOGY
PERFORMING OPERATIONS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
TRANSPORTING
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Summary:The present invention relates to a method for imaging an anatomical structure in a subject in need thereof, comprising the following steps: a) providing an injectable pharmaceutical composition comprising, as a contrast agent, at least one nanoparticle having a mean hydrodynamic diameter below 10 nm and comprising:. a biocompatible matrix, such as polyorganosiloxane,. at least one chelating agent covalently bonded to said biocompatible matrix,. at least one element having a Z of at least 40, chelated to at least a part of the chelating agents, b) injecting an effective amount of said pharmaceutical to said subject, and, c) acquiring an imaging scan of an anatomical structure of said subject in need thereof, by Spectral Photon Counting Computed Tomography (SPCCT) scanning.
Bibliography:Application Number: EP20230793747