VARIANTS OF THERMOSTABLE DNA PRIMASES AND USES THEREOF

The present invention relates to a functionally active mutated primase domain from an archaeal DNA primase belonging to the primase-polymerase family, comprising at least one amino acid substitution, wherein said mutated primase domain retains at least 50% of the template-independent terminal nucleo...

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Bibliographic Details
Main Authors RANDRIANJATOVO-GBALOU, Irina, RAHIER, Renaud, SAID, Ahmed
Format Patent
LanguageEnglish
French
German
Published 23.10.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to a functionally active mutated primase domain from an archaeal DNA primase belonging to the primase-polymerase family, comprising at least one amino acid substitution, wherein said mutated primase domain retains at least 50% of the template-independent terminal nucleotidyl transferase activity of the corresponding wild-type primase domain.
Bibliography:Application Number: EP20220839664