ARTIFICIAL YEAST PROMOTER REGIONS

The invention relates to an artificial yeast promoter region, comprising a TATA box at position -90 ± 15 nucleotides (nt) and/or a TATA box at position -160 ± 15 nt, an enhancer element at position -350 ± 25 nucleotides, and a second enhancer element at position -600 ± 50 nucleotides. The invention...

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Bibliographic Details
Main Authors BAUER, Julia, DIETZ, Heiko, KRACHT, Melissa
Format Patent
LanguageEnglish
French
German
Published 02.10.2024
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Summary:The invention relates to an artificial yeast promoter region, comprising a TATA box at position -90 ± 15 nucleotides (nt) and/or a TATA box at position -160 ± 15 nt, an enhancer element at position -350 ± 25 nucleotides, and a second enhancer element at position -600 ± 50 nucleotides. The invention further relates to an expression construct comprising the artificial yeast promoter region, a yeast host cell, comprising the artificial yeast promoter region, and to methods of producing a protein of interest in a yeast host cell by employing the artificial yeast promoter region.
Bibliography:Application Number: EP20220821503