BISPECIFIC MOLECULE SPECIFICALLY BINDING TO B7-H3 AND TGF? AND USES THEREOF

• Main Authors: LEE, Jung Wook, PARK, Dong Woon, LEE, Jung Eun, JUNG, Byung Hun
• Format: Patent
• Language: English; French; German
• Published: 03.07.2024
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a bispecific molecule including: B7-H3 antibody or antigen-binding fragment thereof; and a TGFβ binding portion bound thereto, more particularly, to a bispecific molecule which is bispecifically bound to B7-H3 and TGFβ and thus can be utilized as an immune checkpoint...