CONTROLLED-RELEASE ORAL PREPARATION AND PREPARATION METHOD THEREFOR

A two-layer controlled-release oral preparation, which comprises a first ingredient as a quick-release layer and a second ingredient as a controlled-release layer, wherein the first ingredient comprises a xanthine derivative, and the second ingredient comprises a xanthine derivative and an enteric e...

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Bibliographic Details
Main Authors LU, Shao Chuan, SU, Yu De, CHUANG, Jwey Yuan
Format Patent
LanguageEnglish
French
German
Published 05.06.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A two-layer controlled-release oral preparation, which comprises a first ingredient as a quick-release layer and a second ingredient as a controlled-release layer, wherein the first ingredient comprises a xanthine derivative, and the second ingredient comprises a xanthine derivative and an enteric excipient. No more than 35% by weight of the xanthine derivative in the second ingredient is released within 90 min after in vitro elution, and 50% or more by weight of the xanthine derivative in the second ingredient is released within 3 h after in vitro elution.
Bibliography:Application Number: EP20210951329